Benefits of intermittent fasting

Current studies conclude that benefits of intermittent fasting have a positive metabolic impact: improving glucose regulation, increasing cell resistance against physiological stress conditions and activating cell repair mechanisms. Conditions that modify the normal course of chronic process like: obesity, diabetes, cardiovascular, cancer and neurodegenerative diseases.

After eating, first our body uses glucose from carbohydrates as an energy resource, and then incorporated fatty acids into our fatty tissue. But during periods of fasting, after spending glucose stores, the body mobilizes fatty tissue, obtaining fatty acids and glycerol, which are converted by the liver into ketone bodies.

Ketone bodies are energy substrate for cells of different tissues like brain, heart or muscles.

Repeated exposure to periods of intermittent fasting results in adaptive responses to stressful situations that result in an increase in the body’s own antioxidant capacity, better effectiveness in DNA repair, greater control of protein quality, mitochondrial optimization and autophagy, as well as greater regulation of inflammatory mechanisms.

Clinical studies have shown that it is an effective intervention to reduce obesity, improve insulin resistance, dyslipidemia, hypertension and inflammation, common conditions in metabolic diseases. The results highlight the positive impact of these modifications in the course of different diseases:

  • A reduction in cardiovascular risk factors, (blood pressure, resting heart rate, HDL and LDL levels, cholesterol, triglycerides, glucose and insulin, and insulin resistance)
  • Difficulty the progression of tumors and optimizing the response to chemotherapy, radiotherapy …
  • Stopping the course of neurodegenerative diseases such as Alzheimer’s disease or Parkinson’s
  • Symptomatic improvement in asthma, multiple sclerosis or arthritis, which correlates with a reduction in inflammatory marker levels and oxidative stress in patients who follow intermittent fasting.

In addition, intermittent pre-surgical fasting has a safe and effective strategy that improves recovery from surgery.

In conclusion, current evidence suggests that intermittent fasting has a broad spectrum of benefits, and that it is a safe and effective nutritional intervention as long as it is supervised by a health professional.

Institut Khuab has an expert multidisciplinary team in the nutritional advice of the patient, who works with personalized goals adapted to the needs of each person. The medical and the nutritional visit with the study of body composition, allow us to design nutritional interventions with intermittent fasting.


by Esther Deltor Head of nutrition department in Khuab Institut

by Esther Deltor Head of nutrition department